Progress in Mind
Choose a channel
Check out the different Progress in Mind content channels.
Towards a novel understanding of Alzheimer’s disease
Read the full article here.
Towards a novel understanding of Alzheimer’s disease
Our correspondent’s highlights from the symposium are meant as a fair representation of the scientific content presented. The views and opinions expressed on this page do not necessarily reflect those of Lundbeck.
References
1 Szaruga M et al. Alzheimer's-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions. Cell. 2017;170:443-56.e14.
2 Gatz M et al. Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry. 2006;63:168-74.
3 Escott-Price V, et al. Polygenic risk score analysis of pathologically confirmed Alzheimer's disease. Ann Neurol. 2017; 82: 311-4.
4 Leonenko G et al. Polygenic risk and hazard scores for Alzheimer's disease prediction Ann Clin Transl Neurol. 2019; 6: 456-65.
5 Sala Frigerio C et al. The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ Plaques. Cell Reports, 2019;27:1293.
6 De Strooper B and Karran E. The cellular phase of Alzheimer’s disease. Cell. 2016;164:603-15.